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Phosphorus balance in ESRD management—the challenges of diet and dialysis

Adequate protein nutrition can come at the expense of controlling phosphorus1

  • Phosphorus balance can be an ongoing challenge in ESRD, because phosphate content in food is closely related to protein content2
  • Providing adequate dietary protein may increase phosphate intake2

Even with KDOQI-recommended dietary phosphorus intake, there is a compelling need for phosphate reduction in dialysis patients

Phosphate binders are a treatment option in the management of positive phosphorus balance6,7

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Indication

FOSRENOL is indicated to reduce serum phosphate in patients with end stage renal disease (ESRD).

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Important Safety Information

Indication

FOSRENOL is indicated to reduce serum phosphate in patients with end stage renal disease (ESRD).

Please click here for Full Prescribing Information.

References: 1. Shinaberger CS, Greenland S, Kopple JD, et al. Is controlling phosphorus by decreasing dietary protein intake beneficial or harmful in individuals with chronic kidney disease? Am J Clin Nutr. 2008;88:1511-1518. 2. Boaz M, Smetana S. Regression equation predicts dietary phosphorus intake from estimate of dietary protein intake. J Am Diet Assoc.1996;96:1268-1270. 3. K/DOQI Clinical Practice Guidelines for Nutrition in Chronic Renal Failure. Am J Kidney Dis. 2000;35(suppl 2):S17-S104. 4. Eknoyan G, Levin A, Levin NW; for the National Kidney Foundation. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am J Kidney Dis. 2003;42(suppl 3):S1-S201. 5. Ramirez JA, Emmett M, White MG, et al. The absorption of dietary phosphorus and calcium in hemodialysis patients. Kidney Int. 1986;30:753-759. 6. Salusky IB, Goodman WG. Managing phosphate retention: is a change necessary? Nephrol Dial Transplant. 2000;15:1738-1742. 7. Finn WF. Phosphorus management in end-stage renal disease. Semin Dial. 2005:18:8-12.