Lanthanum carbonate effectively binds phosphate across the pH range of 3 to 7*1
*The clinical relevance of the effect of pH on in vivo phosphate binding of FOSRENOL® has not been established.
†In vitro binding affinities were calculated using the Langmuir equation and reported as the Langmuir equilibrium constant (K1),which is a measure of the affinity of phosphate for the binder.1
‡Data are from an in vivo rat study.2
